Job Description

Our company's South San Francisco research laboratory is seeking an innovative drug hunter with a strong in vivo background in biology or metabolism to join the cardiometabolic disease department as an Associate Scientist. The individual will perform experiments in the laboratory with minimal guidance and supervision. The successful candidate will design, execute, and interpret complex in vivo/ex vivo/in vitro studies to support target identification, validation, and therapeutic development. The successful candidate will also possess a strong sense of intellectual curiosity to expand their technical expertise at the bench, as well as effective written and interpersonal communication skills to explain complex experiments and biological concepts to a broader scientific team.

Note: This role will be required to work on weekends in a shifted work-week schedule (Tuesday through Saturday).

Key Responsibilities:

• Establish key assays and model systems, suitable for the mechanistic investigation of potential targets, as well as evaluation of therapeutic candidates
• In vivo dosing, bleeding, and handling of small laboratory animals during a shifted work-week that includes the weekend
• Perform molecular biology, cellular biology, cell-based assay, and ex vivo sample processing and analysis
• Design, perform, troubleshoot, document, analyze and interpret assigned research, with minimal supervision, to support exploratory activities as well as project focused goals
• Scour and critically evaluate current literature to identify opportunities for new and existing programs
• Work independently in executing tightly controlled experiments, analyzing data, and presenting to teams within the disease area
• Solve complex problems by undertaking innovative approaches and applying state-of-the art technologies

Qualifications:

Education:

• Bachelors Degree (with 3+ years) or Master's in chemical biology, molecular and cellular biology, pharmacology or other related scientific discipline and relevant experience listed below

Required Experience and Skills:

• Experience in one or more of the following areas: target identification & validation, in-vivo model development, adipose or muscle biology, immunology in the context of metabolic disease is preferred
• Experience with handling, dosing (oral, subcutaneous, intraperitoneal, intravenous), and bleeding small laboratory animals
• Experience working with human as well as pre-clinical tissues and primary cell lines
• Experience with standard molecular biology techniques (western blotting, qPCR, etc...)
• Works independently and is able to simultaneously handle a diverse workload with strong organizational and time management skills
• Strong communication and interpersonal skills as well as the ability to work flexibly in a dynamic team environment
• Scientific curiosity, analytical mindset with a drive to own a project to understand biology, mechanism of action, and drive it through the discovery pipeline

#EligibleforERP

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We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

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U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote".

The Company is required to provide a reasonable estimate of the salary range for this job in certain states and cities within the United States. Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate's relevant skills, experience, and education.

Expected US salary range:

Available benefits include bonus eligibility, long term incentive if applicable, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days. A summary of benefits is listed here.

San Francisco Residents Only:We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only:We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Relocation:

VISA Sponsorship:

Travel Requirements:

Flexible Work Arrangements:

Shift:

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Hazardous Material(s):

Job Posting End Date:

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Requisition ID:R334541