Summary
The National Center for Advancing Translational Sciences (NCATS), is seeking a Senior Scientist to serve as the Director of the Early Translation Branch (ETB), Division of Pre-Clinical Innovation (DPI). The ETB Director is responsible for planning and directing a comprehensive program in the discovery of pharmacological tools to probe the function of the human genome and to understand and improve the processes underlying early discovery.
Duties
The ETB Director is responsible for planning and directing a comprehensive program in the discovery of pharmacological tools to probe the function of the human genome and to understand and improve the processes underlying early discovery. Research areas include the discovery of probe molecules to interrogate biology and de-risk disease hypotheses, using approaches such as high-throughput screening and computational methods, developing innovative methods for assaying the biological activity of novel gene targets and pathways, with a commitment to an open approach to sharing methodologies and data. ETB leverages state-of-the-art discovery resources - including robotic high-throughput screening facilities, compound management, and analytical chemistry - to deliver on this mission.
This position will serve as a senior leader for the science and administration of this large and complex early translation program and serve as the spokesperson for the Branch at conferences and various stakeholder meetings, both nationally and internationally. In consultation with the NCATS Scientific Director (SD), the position is responsible for managing the research portfolio of ETB, ensuring ETB adapts to shifting discovery paradigms where necessary to remain state-of-the-art in its field, and enabling effective partnerships with other programs within DPI and NCATS. In partnership with the NCATS SD, the position is responsible for establishing the goals and objectives for the ETB, ensuring alignment with the goals and objectives determined at higher levels within the Center, and managing a collaborative portfolio of preclinical projects. The position is also responsible for developing long and short-range plans and establishing priorities, determining the resources required to support planned activities, and developing and defending annual budgets for the program.
Requirements
Conditions of Employment
- U.S. Citizenship requirement or proof of being a U.S. National must be met by closing date.
- Employment is subject to the successful completion of a background investigation, verification of qualifications, completion of onboarding forms, submission of required documents, and any other job-related requirement before or after appointment.
- Applicants must meet all qualification requirements by the closing date of this announcement.
- Males born after December 31, 1959 must be registered with the Selective Service.
- Position requires Education. Please provide transcripts.
Qualifications
In order to qualify for a Supervisory Biochemist, GS-0401-15 position you must meet the following requirements:BASIC QUALIFICATIONS:
A. have completed the requirements for a bachelor's degree in a biological science, agriculture, natural resource management, chemistry, or related disciplines appropriate to this position, from an accredited college or university;
OR
B. have a combination of experience and education which includes courses comparable to a major in a biological science, agriculture, natural resource management, chemistry or related disciplines appropriate to this position, AND have appropriate experience or additional education which demonstrates similarly appropriate skills or abilities needed to perform the duties of this position.
ADDITIONAL QUALIFICATIONS: In addition to meeting the education requirements, you must demonstrate in your resume at least one (1) year of qualifying experience equivalent to at least the GS-14 level in the Federal service obtained in either the private or public sector, performing the following types of tasks: directing and managing a large scientifically diverse research program in comprehensive early translational science; working in a multi-disciplinary research environment related to the pre-clinical development of various therapeutic modalities; consolidating research information to generate new strategies and approaches in collaboration with other scientists; overseeing therapeutic development of rare diseases, including small molecule, biologic, and gene therapy approaches; and accomplishing early discovery through the pre-clinical development of therapeutics and diagnostics to proof- of -concept in humans.
IDEAL CANDIDATE:
- Strong background in biomedical sciences as well as a record of accomplishment in academic and/or biopharmaceutical pre-clinical translation, with demonstrated experience leading multidisciplinary research groups in technology and therapeutic/diagnostic/intervention discovery.
- High-level expertise in planning and directing a comprehensive program in early translational science, from target validation through the discovery of pharmacological tools to probe the function of the human genome.
- Proven ability to creatively approach and solve complex technical problems in the preclinical development space.
- Extensive research training and experience in academia, the biopharmaceutical industry, and/or the government. Recognized nationally and internationally for scientific leadership.
- Expertise and accomplishment in multiple aspects of preclinical translation from early discovery through the preclinical development of therapeutics and/or diagnostics to proof-of-concept in humans.
- Has broad and first-hand knowledge of the field of rare disease therapeutic development, including small molecule, biologic, and gene-therapy approaches.
- Evidence of commitment to Diversity, Equity, Inclusion, and Accessibility (DEIA)
To determine your qualifications and referral status, we may review your resume and supporting documentation and compare it against your responses to the vacancy questionnaire. Ensure you support your self-ratings with the information you provide in your application. We may verify or assess your qualifications at any time. Inflated or unsupported qualifications may affect your rating. Any misrepresentation or material omission of facts may be sufficient cause to end further consideration of your candidacy. Persons listed as knowing your past accomplishments or experience in your application may be contacted for verification purposes at any time. Verification may, but need not, begin before receiving an offer.
You will receive credit for all experience material to the position, including experience gained in religious, civic, welfare, service, and organizational activities, regardless of whether you received pay.
Do not copy and paste the duties, specialized experience, or occupational assessment questionnaire from this announcement into your resume as that will not be considered a demonstration of your qualifications for this position.
Preview assessment questionnaire before you apply:
How You Will Be Evaluated
You will be evaluated for this job based on how well you meet the qualifications above.
Additional selections may be made for similar positions across the Department of Health and Human Services (HHS) within the local commuting area(s) of the location identified in this announcement. By applying, you agree to have your application shared with interested selecting official(s) at HHS. Clearance of CTAP/ICTAP will be applied for similar positions across HHS.
The position(s) advertised in this announcement are covered by a direct hire authority. Traditional rating and ranking of applicants, including category rating, does not apply to this vacancy. You will be initially evaluated against the basic qualifications only. Qualified applicants will be referred for consideration in accordance with the . Veterans' Preference does not apply to positions covered by a direct hire authority.
To be considered well qualified for the purposes of the and the , you must be able to satisfactorily perform the duties of the position upon entry and substantively exceed the basic qualifications and meet all eligibility, physical, medical, suitability, and all other requirements.
Required Documents
REQUIRED FOR ALL APPLICANTS
RESUME:
Your resume must thoroughly describe how your skills and experiences align to the criteria defined in the "Qualifications" section of this announcement and it must support your responses to the assessment questionnaire. We cannot assume you have performed the necessary experience required for this position regardless of your employment history or academic career.
To ensure all of the essential information is in your resume, we encourage you to use the r. If you choose to use your own resume, you must ensure it contains all of the required information and you organize it so we can associate the following information for each experience/position:
- Job title
- Name of employer
- Beginning and ending dates of employment (month/day/year format)
- Hours worked per week. We will assume full-time unless otherwise stated. We will prorate part-time employment in crediting experience.
- Detailed description of job duties, accomplishments, related skills, and responsibilities to include any supervisory/managerial responsibilities and number of staff supervised (if applicable)
- Series and grade or equivalent (if a federal position)
Do not include a photograph or video of yourself, or any sensitive information (age, date of birth, marital status, protected health information, religious affiliation, social security number, etc.) on your resume or cover letter. We will not access web pages linked on your resume or cover letter to determine your qualifications.
For resume writing guidance, please visit the following resources: , , and the .
ASSESSMENT QUESTIONNAIRE:
You must submit a completed assessment questionnaire.
Unless otherwise stated, we will only use the information above to determine your qualifications. Not providing the required information may result in a determination that you do not meet minimum requirements for the position (e.g., an ineligible rating) or a lower rating.
REQUIRED DOCUMENTATION FOR CAREER TRANSITION CLAIMS
Visit our websites to claim selection priority through the Career Transition Assistance Program (CTAP) or the Interagency Career Transition Assistance Program (ICTAP):
- CTAP:
- ICTAP:
Please do not submit any other supplementary documentation that is not requested of you. To protect your personal information, we will only send your resume and cover letter to the selecting official or hiring manager.
If you are relying on your education to meet qualification requirements:
Education must be accredited by an accrediting institution recognized by the U.S. Department of Education in order for it to be credited towards qualifications. Therefore, provide only the attendance and/or degrees from .
Failure to provide all of the required information as stated in this vacancy announcement may result in an ineligible rating or may affect the overall rating.
